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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
13.94
Human Site:
Y321
Identified Species:
23.59
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
Y321
A
E
G
S
S
R
D
Y
V
A
V
N
R
S
H
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
Y321
A
E
G
S
S
R
D
Y
V
A
V
N
Q
S
H
Rhesus Macaque
Macaca mulatta
P56490
532
60122
T345
S
S
E
D
A
E
E
T
F
V
K
A
Q
T
E
Dog
Lupus familis
XP_541769
536
61594
Y370
A
E
G
S
V
R
S
Y
V
A
I
N
Q
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
A322
G
D
A
R
G
S
K
A
N
D
Q
T
L
S
Q
Rat
Rattus norvegicus
P31390
486
55674
A320
G
D
V
R
G
S
K
A
N
D
Q
A
L
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
E323
P
L
E
E
A
E
G
E
S
V
P
A
K
R
D
Chicken
Gallus gallus
P30372
466
51547
S312
A
K
D
A
S
Q
I
S
A
S
Q
D
H
L
K
Frog
Xenopus laevis
P30544
484
54107
L329
P
T
Q
S
M
P
P
L
P
A
K
A
N
T
A
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
E368
S
L
A
F
L
Q
S
E
N
T
A
Q
P
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
M361
E
E
T
G
N
V
A
M
K
P
L
S
F
V
R
Honey Bee
Apis mellifera
XP_395477
546
60788
R377
S
Q
Q
L
A
S
I
R
K
R
S
S
L
A
G
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
S335
T
E
G
C
H
S
D
S
I
S
R
S
S
Q
R
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
S483
F
T
V
D
S
V
A
S
K
E
E
L
E
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
0
66.6
N.A.
6.6
6.6
N.A.
0
13.3
13.3
0
N.A.
6.6
0
20
6.6
P-Site Similarity:
100
100
33.3
80
N.A.
13.3
13.3
N.A.
13.3
46.6
20
13.3
N.A.
26.6
33.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
15
8
22
0
15
15
8
29
8
29
0
8
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
15
0
0
22
0
0
15
0
8
0
0
8
% D
% Glu:
8
36
15
8
0
15
8
15
0
8
8
0
8
0
8
% E
% Phe:
8
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% F
% Gly:
15
0
29
8
15
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
15
% H
% Ile:
0
0
0
0
0
0
15
0
8
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
15
0
22
0
15
0
8
0
8
% K
% Leu:
0
15
0
8
8
0
0
8
0
0
8
8
22
8
8
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
22
0
0
22
8
0
0
% N
% Pro:
15
0
0
0
0
8
8
0
8
8
8
0
8
8
0
% P
% Gln:
0
8
15
0
0
15
0
0
0
0
22
8
22
15
22
% Q
% Arg:
0
0
0
15
0
22
0
8
0
8
8
0
8
8
15
% R
% Ser:
22
8
0
29
29
29
15
22
8
15
8
22
8
36
0
% S
% Thr:
8
15
8
0
0
0
0
8
0
8
0
8
0
15
8
% T
% Val:
0
0
15
0
8
15
0
0
22
15
15
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _